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What Is Happening At The Edge Of The Cell Migration?
Ever wondered what's really happening at the edge of your scratch assay? It's more than just an empty gap—it's a bustling frontier of cellular transformation. Cells at the wound edge aren't just sitting there; they are undergoing a profound morphological shift, polarizing their bodies, sprouting sheet-like lamellipodia, and gripping the substrate to pull themselves forward. This isn't an artifact; it's the beautiful, complex biology of cell migration in action.
Aug 115 min read
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Scratch Assay Migration vs Proliferation: Is Your Wound Closure From Cell Proliferation Rather Than Migration?
Struggling to distinguish between cell migration and proliferation in your scratch assays? Uncover the definitive solution with Mitomycin C! This powerful DNA crosslinking agent halts cell division, allowing you to isolate and measure true cell motility with confidence. Our comprehensive guide provides a step-by-step protocol, from preparing your stock solution to analyzing your results, ensuring your wound healing data is both accurate and reproducible.
Jul 115 min read
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