Discover the Latest in Biomedical Research Innovation

Is a RIN score below 7 the end of the road for your sequencing project? Not necessarily. While the "Gold Standard" of RIN > 8 is ideal for Illumina PolyA sequencing, modern techniques have rewritten the rules. From microRNA stability to Ribodepletion strategies for ancient samples, this article explores how to salvage data from degraded RNA. Learn why the RIN 7 cutoff is a myth for certain applications and discover the top 10 ways to improve your RNA isolation before you even

2025 was the year CLYTE evolved from a hardware startup into a biomedical platform. From validating the CytCut device to launching Sophie AI, we achieved ~50k monthly visitors and 5 million impressions with extreme capital efficiency. Discover how we uncovered a massive market gap in lab protocols and secured our place in the future of lab automation.

From antioxidant vitamins and plant flavonoids that mimic cell activity to porphyrins that destroy the signal, many common compounds can skew your data, leading to false positives or negatives. This article explores the specific chemicals that disrupt tetrazolium assays, explains the mechanisms behind these artifacts, and provides essential best practices to ensure your cytotoxicity data is accurate and reproducible.

Are inclusion bodies the bane of your existence or a hidden opportunity? For researchers working with recombinant proteins in E. coli, finding your target protein in an insoluble pellet is a common frustration. But science shows these aggregates are specific, reversible, and often highly pure. This article dives into the mechanisms of protein aggregation, offers proven strategies to prevent it, and provides a step-by-step guide to solubilizing and refolding your protein for m

Scientific research has a plastic problem. Every year, laboratories perform an estimated 3 million "scratch assays" using disposable pipette tips, generating around 200 tons of contaminated plastic waste that cannot be recycled. CytCut offers a solution: a reusable device that eliminates this waste at the source. By replacing single-use tips and improving experimental reproducibility, CytCut cuts carbon footprints by up to 11-fold, proving that science can be rigorous without

Master the MTT assay with this comprehensive guide designed for accuracy and reproducibility. We break down the complex cell viability protocol into actionable steps, focusing on Primary Human Dermal Fibroblasts. Learn how to seed 10,000 cells/well, prepare 6 distinct product concentrations, and precisely measure metabolic activity using formazan detection at 540 nm.

Are you struggling to choose between the cost-effective MTT assay and the visually striking Live/Dead fluorescence staining? This guide breaks down the science, mechanisms, and pros and cons of the two most popular cell viability methods. Whether you are running high-throughput drug screenings or analyzing complex 3D spheroids, understanding the difference between metabolic activity and membrane integrity is key. Dive in to discover which assay reigns supreme for your specifi

CLYTE has officially joined the Google for Startups Cloud Program, a major milestone that validates its proprietary Sophie AI technology. This partnership grants CLYTE access to Google’s advanced computational resources, accelerating the release of Sophie 3.0 in January 2026. With enhanced reliability and deep-context analysis, CLYTE is redefining lab automation. The move sets the stage for a Q1 2026 Seed Round, signaling to investors that CLYTE’s tech stack is scalable and s