Discover the Latest in Biomedical Research Innovation

Most bench scientists reach for a t-test or ANOVA by reflex, but plenty of real experiments have a continuous dose, groups that differ at baseline, or nuisance variation eating the power. Multiple regression handles all three, and ANOVA and ANCOVA turn out to be special cases of it. This guide covers when regression earns its place, how to read coefficients honestly, the two covariate mistakes that invalidate an analysis, and why dose-response needs a 4PL curve, not a line.

The statistics were the easy part; then you lost an afternoon nudging axis labels, adding error bars and significance stars, and redrawing schematics in Illustrator. Sophie's Visualizer, CLYTE's scientific illustration engine, lives in the same chat where you analyze your data, so you just describe the figure you want and get it publication-ready in seconds: data charts, experimental-design schematics, and mechanism diagrams. We walk through turning one finished analysis into